三羧酸载体蛋白SFXN1抗体
规格：1mg/1ml
英文名： SFXN1
别名： FLJ12876; SFXN1; SFXN1_HUMAN; Sideroflexin 1; Sideroflexin-1; TCC; Tricarboxylate carrier protein.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SFXN1
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位：
三羧酸载体蛋白SFXN1抗体产品介绍：background: The sideroflexin (SFXN) family is comprised of SFXN1, SFXN2, SFXN3, SFXN4 and SFXN5. SFXN1, also designated tricarboxylate carrier protein TCC, is the most highly characterized family member. The ubiquitously expressed SFXN1 protein resides as an integral protein of the mitochondrial inner membrane. It functions as an essential component of the shuttle system that transports mitochondrial acetyl-CoA into the cytosol, where lipogenesis occurs. The SFXN1 gene is mutated in flexed-tail (f/f) mice, which display axial skeletal abnormalities and a transient embryonic and neonatal anemia characterized by pathologic intramitochondiral iron deposits in erythrocytes. Therefore, SFXN1 is also thought to facilitate the transport of a component required for iron utilization into mitochondria. All SFXN family三羧酸载体蛋白SFXN1抗体 members show expression in pancreatic islet cells. SFXN5 displays a citrate transport activity and is primarily expressed in brain. Function: Might be involved in the transport of a component required for iron utilization into or out of the mitochondria. Subcellular Location: Mitochondrion membrane. Similarity: Belongs to the sideroflexin family. Gene ID: 94081 Database links: Entrez Gene: 94081 Human三羧酸载体蛋白SFXN1抗体 Entrez Gene: 14057 Mouse Entrez Gene: 364678 Rat GenBank: NM_022754 Human SwissProt: Q9H9B4 Human SwissProt: Q99JR1 Mouse SwissProt: Q63965 Rat Unigene: 369440 Human Unigene: 134191 Mouse Unigene: 115752 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
三羧酸载体蛋白SFXN1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid