钠离子通道调节蛋白1抗体
规格：1mg/1ml
英文名： SCNM1
别名： SCNM 1; Sodium channel modifier 1.
分子量： 26kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SCNM1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
钠离子通道调节蛋白1抗体产品介绍：background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. SCNM1 (sodium channel modifier 1) is a 230 amino acid protein that contains one matrin-type zinc finger. Localized to the nucleus, SCNM1 is thought to function as an RNA splicing factor that may modify the expression of sodium channel-related proteins. SCNM1 exists as two alternatively spliced isoforms that are encoded by a gene which maps to chromosome 1. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the 钠离子通道调节蛋白1抗体human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1 Function: SCNM1 (Sodium channel modifier 1) contains a matrin-type zinc finger. It is thought to function as an RNA splicing factor. It is a disease modifier gene, that modifies phenotypic expression of SCN8A 钠离子通道调节蛋白1抗体mutations in mice and is required for efficient in vivo splicing of a mutant splice donor site in the sodium channel SCN8A. Subcellular Location: Nuclear Database links: Entrez Gene: 79005 Human Omim: 608095 Human SwissProt: Q9BWG6 Human Unigene: 732060 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钠离子通道调节蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid