多梳蛋白SCMH1抗体
规格:1mg/1ml
英文名: SCMH1
别名: Polycomb protein SCMH1; SCMH 1; SCMH1; SCMH1_HUMAN; Scml 3; Scml3; Sex comb on midleg 1; Sex comb on midleg homolog 1.
分子量: 73kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SCMH1
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Cat,
细胞定位:细胞核
多梳蛋白SCMH1抗体产品介绍:background: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Subcellular Location: Nucleus. Tissue Specificity: Strongly expressed in heart, muscle and pancreas.多梳蛋白SCMH1抗体 Weakly expressed in brain, placenta, lung, liver and kidney. Similarity: Belongs to the SCM family. Contains 2 MBT repeats. Contains 1 SAM (sterile alpha motif) domain. Database links: Entrez Gene: 22955 Human Entrez Gene: 29871 Mouse SwissProt: Q96GD3 多梳蛋白SCMH1抗体Human SwissProt: Q8K214 Mouse Unigene: 571874 Human Unigene: 427014 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多梳蛋白SCMH1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid