**珠蛋白相关蛋白1/肺炎分泌蛋白1抗体
规格：1mg/1ml
英文名： SCGB3A2
别名： LU103; Pneumo secretory protein 1; PnSP-1; PNSP1; Secretoglobin family 3A member 2; UGRP1; Uteroglobin-related protein 1.
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SCGB3A2
交叉反应：Human, Mouse, Rat,
细胞定位：分泌型蛋白
**珠蛋白相关蛋白1/肺炎分泌蛋白1抗体产品介绍：background: Uteroglobin-related protein 1 is a 93-amino acid secretory protein that is mainly expressed in lung Clara-like epithelial cells, with low levels of expression in the thyroid. The homodimeric UGRP1 may play an anti-inflammatory role in lung inflammation, though the mechanism is still unknown. A macrophage scavenger receptor with collagenous structure (MARCO) acts as a receptor for UGRP1 and may be involved in pathogen clearance in the lung. UGRP1 has a binding site for bacterial lipopolysaccharide (LPS). It is downregulated in antigen-induced inflamed airways, such as allergic asthma, but is upregulated in cystic fibrosis,**珠蛋白相关蛋白1/肺炎分泌蛋白1抗体 and interleukin-9 and interleukin-5 modulate UGRP1 expression. UGRP1 may be a therapeutic candidate for treating various sources of lung inflammation Function: In addition to regulating thyroid-specific expression of genes, thyroid transcription factor controls the transcription of genes specifically expressed in lung, such as surfactant proteins and uteroglobin. Mice lacking Ttf1 die immediately after birth from respiratory failure caused by profoundly hypoplastic lungs. The UGRP1 gene encodes a uteroglobin-related protein and is a downstream **珠蛋白相关蛋白1/肺炎分泌蛋白1抗体target of TITF1. Subcellular Location: Secreted. Database links: Entrez Gene: 117156 Human Omim: 606531 Human SwissProt: Q96PL1 Human Unigene: 483765 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
**珠蛋白相关蛋白1/肺炎分泌蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid