突触结合蛋白1样2抗体
规格：1mg/1ml
英文名： SCFD1
别名： C14orf163; Chromosome 14 open reading frame 163; RA410; Scfd1; SCFD1_HUMAN; Sec1 family domain containing 1; Sec1 family domain-containing protein 1; SLY1; SLY1 homolog; Sly1p; STXBP1L2; Syntaxin bind
分子量： 72kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SCFD1
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Guinea Pig, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Orangutan, Elephant
细胞定位：细胞浆
突触结合蛋白1样2抗体产品介绍：background: SCFD1 is a 642 amino acid protein that belongs to the STXBP/unc-18/SEC1 family. Phosphorylated upon DNA damage, probably by Atm or ATR, SCFD1 is involved in vesicular transport between the endoplasmic reticulum (ER) and the Golgi. The SCFD1 protein plays a role in SNARE-pin assembly and Golgi to ER retrograde transport via its interaction with COG4. The SCFD1 protein also binds Syntaxin 5. The SCFD1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, mosquito, Drosophila, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana and rice, and maps to human chromosome 14q12. Deletion of a region of chromosome 14 that contains BF-1, PKC ? SCFD1, Cochlin and SG2NA genes, is responsible for a condition resulting in severe mental 突触结合蛋白1样2抗体retardation, epilepsy, microcephaly and Rett-like features. Function: Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi. Subcellular Location: Cytoplasm. Endoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Post-translational modifications: Phosphorylated upon突触结合蛋白1样2抗体 DNA damage, probably by ATM or ATR. Similarity: Belongs to the STXBP/unc-18/SEC1 family. Database links: Entrez Gene: 100140328 Cow Entrez Gene: 480281 Dog Entrez Gene: 23256 Human Entrez Gene: 76983 Mouse Entrez Gene: 54350 Rat SwissProt: Q8WVM8 Human SwissProt: Q8BRF7 Mouse SwissProt: Q62991 Rat Unigene: 369168 Human Unigene: 216511 Mouse Unigene: 10761 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触结合蛋白1样2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid