肿瘤细胞转移抑制蛋白抗体
规格:1mg/1ml
英文名: SCAI
别名: C9orf126; FLJ11758; FLJ36664; MGC120525; MGC120526; MGC120528; NET40; Protein SCAI; SCAI; SCAI_HUMAN; Suppressor of cancer cell invasion; Suppressor of cancer cell invasion protein.
分子量: 70kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SCAI
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
细胞定位:细胞核 细胞浆 细胞膜
肿瘤细胞转移抑制蛋白抗体member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010] Function: Tumor suppressor which functions to suppress MKL1-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1. Subunit: Interacts with DIAPH1 (By similarity). Forms a nuclear ternary complex with MKL1 and SRF. Subcellular Location:肿瘤细胞转移抑制蛋白抗体 Membrane. Nucleus. Cytoplasm. Nuclear localization is required for inhibition of MKL1. Similarity: Belongs to the SCAI family. Gene ID: 286205 Database links: Entrez Gene: 286205 Human Entrez Gene: 320271 Mouse Entrez Gene: 690538 Rat 肿瘤细胞转移抑制蛋白抗体SwissProt: Q8N9R8 Human SwissProt: Q8C8N2 Mouse Unigene: 59504 Human Unigene: 204836 Mouse Unigene: 206053 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤细胞转移抑制蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 细胞类型标志物 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid