锚蛋白重复结构域47抗体
规格：1mg/1ml
英文名： ANKRD47
别名： ANKRD47; Ankyrin repeat domain 47; Ankyrin repeat domain containing protein 47; Ankyrin repeat domain-containing protein 47; FLJ46061; KANK3; KANK3_HUMAN; Kidney ankyrin repeat containing protein 3; K
分子量： 86kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ANKRD47
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig,
细胞定位：
锚蛋白重复结构域47抗体产品介绍：background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD47 an 840 amino acid coiled-coil protein that contains five ANK repeats and exists as two alternatively spliced isoforms. Conserved in chimpanzee, dog, cow, mouse and rat, ANKRD47 is expressed in breast, liver, lung, skeletal muscle and kidney. ANKRD47 assists in the formation of actin stress fibers and is encoded by a gene that maps to human chromosome 19p13.2.锚蛋白重复结构域47抗体 Chromosome 19 makes up over 2% of the human genome and contains approximately 63 million bases, which encode over 1,400 genes. Recognized for having the greatest gene density of all human chromosomes, chromosome 19 is linked to Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes Function: May be involved in the control of cytoskeleton formation by regulating actin polymerization. Tissue Specificity: Strongly expressed in breast, liver, lung, skeletal muscle 锚蛋白重复结构域47抗体and kidney. Similarity: Contains 5 ANK repeats. Database links: Entrez Gene: 256949 Human Entrez Gene: 80880 Mouse Entrez Gene: 366848 Rat Omim: 614611 Human SwissProt: Q6NY19 Human SwissProt: Q9Z1P7 Mouse Unigene: 322473 Human Unigene: 196330 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锚蛋白重复结构域47抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid