JOSD2蛋白抗体
规格：1mg/1ml
英文名： Josephin-2
别名： FLJ29018; JOS2_HUMAN; JOSD 2; JOSD2; Josephin 2; Josephin domain containing 2; Josephin domain containing protein 2; Josephin domain-containing protein 2; Josephin-2; Josephin2; SBBI54.
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Josephin
交叉反应：Human, Mouse, Rat, Dog, Cow, Guinea Pig, Cat,
细胞定位：
JOSD2蛋白抗体产品介绍：background: Josephin-2, also known as JOSD2 (josephin domain containing 2), is a 188 amino acid protein that contains one josephin domain and is encoded by a gene that maps to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc?receptors.JOSD2蛋白抗体 Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. Function: CleavesJOSD2蛋白抗体 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme. Similarity: Contains 1 Josephin domain. Database links: Entrez Gene: 611845 Dog Entrez Gene: 126119 Human Entrez Gene: 66124 Mouse Entrez Gene: 292876 Rat SwissProt: Q8TAC2 Human SwissProt: Q9CR30 Mouse Unigene: 467151 Human Unigene: 358691 Mouse Unigene: 22861 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
JOSD2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 表观遗传学 泛素
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid