JMJD4蛋白抗体
规格：1mg/1ml
英文名： JMJD4
别名： 6430559I23; AU020939; JmjC domain containing protein 4; JmjC domain-containing protein 4; JMJD 4; JMJD4; JMJD4_HUMAN; Jumonji domain containing 4; Jumonji domain-containing protein 4; RGD1307186; R
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human JMJD4
交叉反应：Human, Mouse, Rat,
细胞定位：
JMJD4蛋白抗体产品介绍：background: A crucial regulator of chromatin dynamics and DNA transcription is the covalent modification and methylation of histones. Generally, methylation of certain lysine residues on Histone H3 and Histone H4 can be associated with transcriptionally active or inactive chromatin. This regulation has profound effects on the expression of genes and is part of an epigenetic memory network that determines cell fate. JMJD4 (Jumonji domain-containing protein 4) is a member of a family of JMJC domain-containing histone JMJD4蛋白抗体demethylases that are directly involved in removing methyl residues from distinct and unique lysine residues. These actions are implicated in gene expression and the regulation of cell senescence. JMJC domain-containing histone demethylases are also likely involved in development via their ability to regulate gene expression. Similarity: Contains 1 JmjC domain. Database links: Entrez Gene: 65094 Human Entrez Gene: JMJD4蛋白抗体287359 Rat SwissProt: Q9H9V9 Human Unigene: 555974 Human Unigene: 729813 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
JMJD4蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid