电压门控离子通道蛋白TPGS1抗体
规格：1mg/1ml
英文名： TPGS1
别名： C19orf20; two pore segment channel 1; Gene trap ROSA b geo 22; GTRGEO22; PGs1; Tubulin polyglutamylase complex subunit 1.
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TPGS1
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
细胞定位：
电压门控离子通道蛋白TPGS1抗体产品介绍：background: TPCN1 is a widely expressed, 816 amino acid voltage-gated cation channel protein with predominant expression in lung, liver, heart and kidney. In the kidney, TPCN1 localizes to the inner medullary collecting ducts. In contrast with the distantly related four-domain voltage-gated calcium and sodium channels and the more closely related four-domain ion transport protein located on the surface of sperm cells (CatSper), TPCN1 is a two-domain channel. Similar to the four-domain channel structure,电压门控离子通道蛋白TPGS1抗体 each of the two homologous domains that comprise TPCN1 contains six transmembrane segments (S1-S6) with a pore loop between S5 and S6 and a voltage sensor segment that is positively charged. TPCN1 has hydrophilic N- and C-termini that localize to the cytoplasm. Function: TPGS1 may act in the targeting of the tubulin polyglutamylase complex. It is required for the development of the spermatid flagellum. Subunit: Part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1. Subcellular 电压门控离子通道蛋白TPGS1抗体Location: Microtubule. Gene ID: 91978 Database links: Entrez Gene: 91978 Human Entrez Gene: 110012 Mouse SwissProt: Q6ZTW0 Human SwissProt: Q99MS8 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
电压门控离子通道蛋白TPGS1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 通道蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid