原肌球蛋白调节蛋白1抗体
规格:1mg/1ml
英文名: Tropomodulin 1
别名: D9S57E; E Tmod; E tropomodulin; E-Tmod; Erythrocyte tropomodulin; ETMOD; MGC124125; MGC124126; OTTHUMP00000021743; TMOD; Tmod1; TMOD1 protein; TMOD1_HUMAN; Tropomodulin 1; Tropomodulin-1.
分子量: 41kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Tropomod
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,
细胞定位:细胞浆 细胞膜
原肌球蛋白调节蛋白1抗体产品介绍:background: This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009] Function: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of原肌球蛋白调节蛋白1抗体 the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. Subunit: Binds to the N-terminus of isoforms 2/3 of TPM3 and to actin. Subcellular Location: Cytoplasm > cytoskeleton. Tissue Specificity: Highly expressed in the erythrocyte, heart and skeletal muscle. Similarity: Belongs to the 原肌球蛋白调节蛋白1抗体tropomodulin family. Gene ID: 7111 Database links: Entrez Gene: 7111 Human Omim: 190930 Human SwissProt: P28289 Human Unigene: 404289 Human Unigene: 494595 Human Unigene: 723236 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原肌球蛋白调节蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 结合蛋白 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid