TRMT1蛋白抗体
规格：1mg/1ml
英文名： TRMT1
别名： TRM1; 2)G26)dimethyltransferase; 2-dimethylguanosine-26 methyltransferase; FLJ20244; N(2) N(2) dimethylguanosine tRNA methyltransferase; N(2)-N(2)) methyltransferase; TRM 1; TRM1 tRNA methyltransferas
分子量： 72kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TRMT1
交叉反应：Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位：
TRMT1蛋白抗体产品介绍：background: Transfer RNA (tRNA) modifications help regulate the efficiency of mRNA translation by maintaining the correct reading frames. N(2),N(2)-dimethylguanosine tRNA methyltransferase, also known as TRMT1 or tRNA(guanine-26,N(2)-N(2)) methyltransferase, is a 659 amino acid enzyme that is responsible for tRNA modifications in eukaryotes. Using S-adenosyl-L-methionine as a methyl donor, TRMT1 dimethylates a single guanine residue at position 26 of tRNA. TRMT1, which was initially identified in yeast and C. elegans, has a 26% and 31% sequence identity to its yeast and C. elegans homologs, respectively. There are two isoforms of TRMT1 produced by TRMT1蛋白抗体alternative splicing events. The TRMT1 gene maps to chromosome 19p13.13 and mutations in this gene lead to abrogated enzyme activity and a decrease in protein levels. Function: Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups. Similarity: Contains 1 C3H1-type zinc finger. Gene ID: 55621 Database links: Entrez Gene: 55621 Human Entrez TRMT1蛋白抗体Gene: 212528 Mouse Entrez Gene: 288914 Rat Omim: 611669 Human SwissProt: Q9NXH9 Human SwissProt: Q3TX08 Mouse Unigene: 515169 Human Unigene: 275720 Mouse Unigene: 17073 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
TRMT1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid