TRIM66蛋白抗体
规格:1mg/1ml
英文名: TRIM66
别名: TRI66_HUMAN; Trim66; Tripartite motif-containing protein 66.
分子量: 135kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TRIM66
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核
TRIM66蛋白抗体产品介绍:Function: May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association. Subunit: Can form homodimers and heterodimers. Interacts with CBX5, CBX1 and CBX3 via PxVxL TRIM66蛋白抗体motif (By similarity). Subcellular Location: Nucleus. Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm. Similarity: Contains 2 B box-type zinc fingers. Contains 1 bromo domain. Contains 1 PHD-type zinc finger. Gene ID: 9866 Database links:TRIM66蛋白抗体 Entrez Gene: 9866 Human Omim: 612000 Human SwissProt: O15016 Human Unigene: 130836 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
TRIM66蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid