L型氨基酸转运蛋白3抗体
规格:1mg/1ml
英文名: LAT3
别名: L type amino acid transporter 3; L-type amino acid transporter 3; Large neutral amino acids transporter small subunit 3; LAT3_HUMAN; PB39; POV1; Prostate cancer overexpressed gene 1 protein; R00504; S
分子量: 61kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LAT3
交叉反应:Human, Mouse, Rat, Cow, Horse, Rabbit,
细胞定位:细胞膜
L型氨基酸转运蛋白3抗体产品介绍:background: SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008] Function: Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer. Subcellular Location: Membrane. Tissue Specificity: In *****s, found in all tissues examined with highest L型氨基酸转运蛋白3抗体expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells. Similarity: Belongs to the SLC43A transporter (TC 2.A.1.44) family. Gene ID: 8501 Database links: Entrez Gene: 8501 Human L型氨基酸转运蛋白3抗体Omim: 603733 Human SwissProt: O75387 Human Unigene: 591952 Human Unigene: 735724 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
L型氨基酸转运蛋白3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid