KATNAL1蛋白抗体
规格:1mg/1ml
英文名: KATNAL1
别名: Katanin p60 AL1; Katanin p60 ATPase containing subunit A like 1; Katanin p60 ATPase-containing subunit A-like 1; Katanin p60 subunit A like 1; Katanin p60 subunit A-like 1; KATL1_HUMAN; KATNAL1; MGC25
分子量: 55kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KATNAL1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
细胞定位:细胞浆
KATNAL1蛋白抗体产品介绍:background: Microtubules are polymers of alpha and beta subunits that form the mitotic spindle and assist in the organization of membranous organelles during interphase. Katanin is a heterodimer complex that severs microtubules in an ATP-dependent manner. The severing of microtubules by the Katanin complex may promote reorganization of cellular microtubule arrays and release of microtubules from the centrosome following nucleation. The Katanin complex is composed of a 60 kDa subunit (Katanin p60 A1) and a 80 kDa accessory protein (Katanin p80 B1). Katanin p60 A1 is responsible for the severing and disassembly of microtubules, while Katanin p80 B1 targets the complex to the centrosome. Katanin p60 A1 and Katanin p80 B1 belong to the AAA ATPase family, which also includes the KATNAL1蛋白抗体Katanin p60 A1-like proteins, Katanin p60 AL1 and Katanin p60 AL2. Function: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. Subcellular Location: Cytoplasm; cytoskeleton. SimilarityKATNAL1蛋白抗体: Belongs to the AAA ATPase family. Gene ID: 84056 Database links: Entrez Gene: 84056 Human Entrez Gene: 231912 Mouse Entrez Gene: 288449 Rat Omim: 614764 Human SwissProt: Q9BW62 Human SwissProt: Q8K0T4 Mouse SwissProt: Q5XIK7 Rat Unigene: 243596 Human Unigene: 397405 Mouse Unigene: 208215 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KATNAL1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid