驱动蛋白家族成员26A抗体
规格：1mg/1ml
英文名： KIF26A
别名： DKFZP434N178; FLJ22753; KI26A_HUMAN; KIAA1236; KIF 26A; KIF26A; KIF26A variant protein; Kinesin family member 26A; Kinesin like protein KIF26A; Kinesin-like protein KIF26A.
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIF26A
交叉反应：Human,
细胞定位：
驱动蛋白家族成员26A抗体产品介绍：background: The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF26A (kinesin family member 26A) is a 1,882 amino acid protein that contains one N-terminal kinesin-motor domain and belongs to驱动蛋白家族成员26A抗体 the kinesin-like protein family. The kinesin-motor domain is responsible for the ATP-dependent movement of KIF26A across microtubules. Function: Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity. Subcellular Location: Cytoplasm > cytoskeleton. 驱动蛋白家族成员26A抗体Similarity: Belongs to the kinesin-like protein family. KIF26 subfamily. Contains 1 kinesin-motor domain. Database links: Entrez Gene: 26153 Human Omim: 613231 Human SwissProt: Q9ULI4 Human Unigene: 134970 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
驱动蛋白家族成员26A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid