驱动蛋白家族成员24抗体
规格：1mg/1ml
英文名： KIF24
别名： bA571F15.4; C9orf48; Kif24; KIF24_HUMAN; kinesin family member 24; Kinesin-like protein KIF24; RP11-571F15.7.
分子量： 152kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIF24
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞浆
产品介绍：background: Kinesins, such as KIF24, are microtubule-dependent ATPases that function as molecular motors. They play important roles in 驱动蛋白家族成员24抗体intracellular vesicle transport and cell division (summary by Venturelli et al., 2010 [PubMed 20670673]).[supplied by OMIM, Feb 2011] Function: Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization 驱动蛋白家族成员24抗体of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. Subunit: Interacts with CCP110 and CEP97. Subcellular Location: Cytoplasm; cytoskeleton. Similarity: Belongs to the kinesin-like protein family. Contains 1 kinesin-motor驱动蛋白家族成员24抗体 domain. Contains 1 SAM (sterile alpha motif) domain. Gene ID: 347240 Database links: Entrez Gene: 347240 Human Omim: 613747 Human SwissProt: Q5T7B8 Human Unigene: 710246 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
驱动蛋白家族成员24抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid