驱动蛋白家族成员18A抗体
规格：1mg/1ml
英文名： KIF18A
别名： AU024633; B130001M12Rik; DKFZp434G2226; KI18A_HUMAN; KIF 18A; KIF18A; kinesin family member 18A; Kinesin like protein KIF18A; Kinesin-like protein KIF18A; Marrow stromal KIF18A; MGC27627; MS KIF18A; M
分子量： 102kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIF18A
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Chimpanzee,
细胞定位：细胞核 细胞浆
驱动蛋白家族成员18A抗体产品介绍：background: KIF18A is a 898 amino acid protein that contains one kinesin-motor domain, which is responsible for the ATP-dependent movement of KIF18A across microtubules. KIF18A plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. Expression of KIF18A is induced by estrogen. Function: Microtubule-depolymerizing kinesin which plays a role in chromosome congression 驱动蛋白家族成员18A抗体by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. Subcellular Location: Cell projection > ruffle. Cytoplasm. Nucleus. Cytoplasm > cytoskeleton > 驱动蛋白家族成员18A抗体centrosome. Post-translational modifications: Glycosylated. Ubiquitinated. Similarity: Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. Gene ID: 81930 Database links: Entrez Gene: 81930 Human Omim: 611271 Human SwissProt: Q8NI77 Human Unigene: 301052 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
驱动蛋白家族成员18A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid