KIAA2022蛋白抗体
规格：1mg/1ml
英文名： KIAA2022
别名： Protein KIAA2022; expressed sequence C77370; K2022_HUMAN; Kiaa2022; RP11-130N24.1; RP23-35L3.1; Uncharacterized protein KIAA2022.
分子量： 167kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Protein
交叉反应：Human, Mouse, Rat, Pig, Horse,
细胞定位：细胞核
KIAA2022蛋白抗体产品介绍：background: KIAA2022 is a 1,516 amino acid protein that is highly expressed in both ***** and fetal brain and is encoded by a gene which maps to human chromosome X. Chromosomal aberrations involving the KIAA2022 gene are associate with the development of severe mental retardation, suggesting a role for KIAA2022 in normal brain development and function. Human chromosome X, on which the KIAA2022 gene is localized, contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination KIAA2022蛋白抗体of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy. Tissue Specificity: Highly expressed in fetal and ***** brain, predominantly in the cerebral cortex and the cerebellum. Also expressed in other tissues but to a lesser extent. DISEASE: Note=A chromosomal aberration involving KIAA2022 is found in 2 patients with severe mental retardation (MR). Pericentric inversion inv(X)(p22.3;q13.2). The Xq13 breakpoint lies within a predicted intron of KIAA2022 gene. KIAA2022 protein is no longer expressed inKIAA2022蛋白抗体 these patients lymphocytes. Gene ID: 340533 Database links: Entrez Gene: 340533 Human Omim: 300524 Human SwissProt: Q5QGS0 Human Unigene: 124128 Human Entrez Gene: 100173017 Orangutan Entrez Gene: 100155718 Pig Entrez Gene: 716288 Rhesus monkey Omim: 607359 Human SwissProt: Q8N163 Human SwissProt: Q8VDP4 Mouse SwissProt: Q5R8S0 Orangutan Unigene: 433722 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KIAA2022蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 发育生物学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid