阶段特异性胚胎表面抗原-1抗体
规格：1mg/1ml
英文名： CD15
别名： Fut4; SSEA-1; 3-FAL; Alpha (1,3) fucosyltransferase; Alpha 13 fucosyltransferase FucT; EC 2.4.1.; ELAM 1 ligand fucosyltransferase; ELAM ligand fucosyltransferase; ELAM1 ligand fucosyltransferase; ELF
分子量： 58(hu)/49(mo, rakDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD15
交叉反应：Human, Mouse, Rat,
细胞定位：
阶段特异性胚胎表面抗原-1抗体cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]. Function: May catalyze alpha-1,3 glycosidic linkages involved in the expression阶段特异性胚胎表面抗原-1抗体 of Lewis X/SSEA-1 and VIM-2 antigens. Subcellular Location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi. Tissue Specificity: Highest expression in stomach and colon. It is also expressed in the lung, testis, uterus, small intestine and to a lesser extent in spleen, and ovary. Present in trace amounts in brain, thymus, heart, smooth muscle, kidney and bone marrow. Not found in liver, salivary gland and pancreas. Similarity: Belongs to the glycosyltransferase 10 family. Gene ID: 2526 Database links: Entrez Gene: 10690 Human Entrez Gene: 2526 Human Entrez Gene: 2527 Human Entrez Gene: 2528 Human Entrez Gene: 2529 Human Omim: 104230 Human SwissProt: P22083 Human SwissProt: P51993 Human SwissProt: Q11128 Human SwissProt: Q11130 Human SwissProt: 阶段特异性胚胎表面抗原-1抗体Q9Y231 Human Unigene: 390420 Human Unigene: 457 Human Unigene: 49117 Human Unigene: 572064 Human Unigene: 623098 Human Unigene: 631843 Human Unigene: 631846 Human Unigene: 705615 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD15(SSEA-1)是胚胎干细胞表达胚胎阶段特异性抗原的主要SSEA-1蛋白,还包括、SSEA-3、TRA-1-81、TRA-1-60等。CD15主要存在于粒细胞（包括中性粒细胞和嗜酸性粒细胞）以及部分单核细胞上。它在介导细胞吞噬**和趋化性方面起重要作用。CD15常表达于霍奇金氏病中R-S细胞，尤其是经典型霍奇金**瘤中。结节硬化型霍奇金**瘤多为CD15阳性。CD15抗体是鉴定霍奇金氏病的一个有效工具。
阶段特异性胚胎表面抗原-1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid