防御素α1/3抗体
规格:1mg/1ml
英文名: DEFA1/alpha Defensin 1
别名: Defensin, alpha 1; alpha Defensin 1/3; alpha Defensin 1+3; ; Defensin alpha 3; HNP1; HNP3; HP1; DEF1_HUMAN; Neutrophil defensin 1; HNP-1; HP-1; HP1; HP 1-56; Neutrophil defensin 1; Neutrophil defensin
分子量: 6.7kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human alpha De
交叉反应:Human,
细胞定位:分泌型蛋白
防御素α1/3抗体产品介绍:background: Defensins are a group of cyclic peptides containing 29-35 amino acids, which comprise approximately 30% of the total protein content of neutrophil azurophilic granules. Various functions have been reported for the defensins, including antibacterial and antifungal activity and chemotactic activity for monocytes. Function: Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes 防御素α1/3抗体by permeabilizing their plasma membrane. Subunit: Dimer. Subcellular Location: Secreted. Post-translational modifications: ADP-ribosylation drastically reduces cytotoxic and antibacterial activities, and enhances IL8 production. Phosphorylation at Tyr-85 has been found in some cancer cell lines, and interferes with ADP-rybosylation. Similarity: Belongs to the alpha-defensin family. Gene ID: 1667 1668 Database links: 防御素α1/3抗体Entrez Gene: 1667 Human Entrez Gene: 1668 Human Entrez Gene: 728358 Human Entrez Gene: 13216 Mouse Omim: 125220 Human SwissProt: P59665 Human SwissProt: P59666 Human SwissProt: P11477 Mouse Unigene: 380781 Human Unigene: 654448 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
防御素α1/3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid