电压门控钾通道亚基KV9.3抗体
规格:1mg/1ml
英文名: KCNS3
别名: Delayed rectifier K(+) channel alpha subunit 3; Delayed rectifier K+ channel alpha subunit 3; Delayed-rectifier K(+) channel alpha subunit 3; KCNS 3; Kcns3; KCNS3_HUMAN; KV 9.3; KV9.3; MGC9481; Potass
分子量: 56kDa
存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KCNS3
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep,
细胞定位:细胞膜
电压门控钾通道亚基KV9.3抗体产品介绍:background: Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively 电压门控钾通道亚基KV9.3抗体spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013] Function: Potassium channel subunit. Modulates channel activity and reduces the ion flow. Subunit: Heteromultimer with KCNB1 and with KCNB2. Does not form homomultimers. Might also bind to other channel proteins (By similarity). Subcellular Location: Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1. Tissue Specificity: Detected in most tissues, but not in peripheral blood 电压门控钾通道亚基KV9.3抗体lymphocytes. The highest levels of expression are in lung. Similarity: Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily. Gene ID: 3790 Database links: Entrez Gene: 3790 Human Entrez Gene: 238076 Mouse Entrez Gene: 83588 Rat Omim: 603888 Human SwissProt: Q9BQ31 Human SwissProt: Q8BQZ8 Mouse SwissProt: O88759 Rat Unigene: 414489 Human Unigene: 113278 Mouse Unigene: 10878 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
电压门控钾通道亚基KV9.3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 通道蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid