电导钙激活钾通道蛋白2抗体
规格：1mg/1ml
英文名： KCNN2
别名： Apamin sensitive small conductance Ca2+ activated potassium; Apamin sensitive small conductance Ca2+ activated potassium channel; hSK2; KCa2.2; Kcnn2; KCNN2_HUMAN; Potassium intermediate/small conduct
分子量： 64kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KCNN2
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
电导钙激活钾通道蛋白2抗体产品介绍：background: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants电导钙激活钾通道蛋白2抗体. [provided by RefSeq, May 2013] Function: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. Subcellular Location: Membrane. Tissue Specificity: Widely expressed. Similarity: Belongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily. Gene ID: 3781 Database links: Entrez Gene: 3781 Human Entrez电导钙激活钾通道蛋白2抗体 Gene: 395579 Chicken Entrez Gene: 404177 Cow Entrez Gene: 474640 Dog Entrez Gene: 140492 Mouse Entrez Gene: 54262 Rat Omim: 605879 Human SwissProt: Q6PJI0 Human SwissProt: Q9H2S1 Human SwissProt: P58390 Mouse SwissProt: Q3UF29 Mouse SwissProt: Q540U9 Mouse SwissProt: Q80X11 Mouse SwissProt: Q8C7F3 Mouse SwissProt: Q8CAD4 Mouse SwissProt: Q8CCH4 Mouse SwissProt: P70604 Rat Unigene: 98280 Human Unigene: 458654 Mouse Unigene: 44421 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
电导钙激活钾通道蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid