电导钙激活钾通道蛋白1抗体
规格：1mg/1ml
英文名： KCNN1
别名： hSK1; KCa2.1; KCNN 1; KCNN 1; Kcnn1; KCNN1_HUMAN; Potassium intermediate/small conductance calcium activated channel subfamily N member 1; SK; SK1; SKCa 1; SKCA1; Small conductance calcium activated p
分子量： 60kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KCNN1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞膜
电导钙激活钾通道蛋白1抗体产品介绍：background: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits电导钙激活钾通道蛋白1抗体. This gene is a member of the KCNN family of potassium channel genes. [provided by RefSeq, Jul 2008] Function: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization电导钙激活钾通道蛋白1抗体. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. Subcellular Location: Membrane. Similarity: Belongs to the potassium channel KCNN family. KCa2.1/KCNN1 subfamily. Gene ID: 3780 Database links: Entrez Gene: 3780 Human Entrez Gene: 84036 Mouse Entrez Gene: 54261 Rat Omim: 602982 Human SwissProt: Q92952 Human SwissProt: Q9EQR3 Mouse SwissProt: P70606 Rat Unigene: 158173 Human Unigene: 32074 Mouse Unigene: 44422 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
电导钙激活钾通道蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid