甲型流感病毒血凝素抗体
规格：1mg/1ml
英文名： H2N2 Hemagglutinin
别名： hemagglutinin [Influenza A virus (A/Chile/6/57 (H2N2))]; HA; Hemagglutinin; Hemagglutinin HA1 chain; Hemagglutinin HA2 chain.
分子量： 62kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from hemagglutinin
交叉反应：Influenza Avirus H2N2
细胞定位：
甲型流感病毒血凝素抗体产品介绍：background: No data available. Function: Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion甲型流感病毒血凝素抗体 pore. Subunit: Homotrimer of disulfide-linked HA1-HA2. Subcellular Location: Virion membrane; Single-pass type I membrane protein (Potential). Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant甲型流感病毒血凝素抗体 lipid rafts. Post-translational modifications: In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoprotease secreted by the bronchial epithelial cells. One identified protease that may be involved in this process is secreted in lungs by Clara cells (By similarity). Palmitoylated. Similarity: Belongs to the influenza viruses hemagglutinin family. Database links: UniProtKB/Swiss-Prot: P03451.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甲型流感病毒血凝素抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 **及病毒
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid