KCNH7蛋白抗体
规格：1mg/1ml
英文名： KCNH7
别名： 9330137I11Rik; eag related protein 3; ERG3; Ether a go go related gene potassium channel 3; HERG3; Kv11.3; Potassium channel subunit HERG 3; Potassium voltage channel subfamily H (eag-related) member
分子量： 105kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KCNH7
交叉反应：Human,
细胞定位：细胞膜
KCNH7蛋白抗体产品介绍：background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008] Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Subunit: The potassium channel is probablyKCNH7蛋白抗体 composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH2/ERG1 and KCNH6/ERG2 (By similarity). Subcellular Location: Membrane; Multi-pass membrane protein Tissue Specificity: Expressed in prolactin-secreting adenomas. Similarity: Belongs to the potassium channel family. Contains 1 cyclic nucleotide-binding domain.KCNH7蛋白抗体 Contains 1 PAC (PAS-associated C-terminal) domain. Contains 1 PAS (PER-ARNT-SIM) domain. Gene ID: 90134 Database links: Entrez Gene: 90134 Human Entrez Gene: 170738 Mouse Entrez Gene: 170739 Rat Omim: 608169 Human SwissProt: Q4ZHQ8 Guinea pig SwissProt: Q9NS40 Human SwissProt: Q9ER47 Mouse SwissProt: O54852 Rat Unigene: 657413 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KCNH7蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid