KREMEN1蛋白抗体
规格：1mg/1ml
英文名： KREMEN1
别名： AV002070; Dickkopf receptor; KREM1_HUMAN; KREMEN; Kremen protein 1; Kremen protein 1 precursor; Kremen1; Kringle coding gene marking the eye and the nose; Kringle containing protein marking the eye an
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KREMEN1
交叉反应：Human, Mouse, Rat, Cow, Sheep,
细胞定位：细胞膜
KREMEN1蛋白抗体产品介绍：background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.KREMEN1蛋白抗体 [provided by RefSeq, Jul 2008] Function: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). {ECO:0000250}. Subcellular Location: Membrane {ECO:0000305}; Single-pass type I membrane protein KREMEN1蛋白抗体{ECO:0000305}. Similarity: Contains 1 CUB domain. Gene ID: 83999 Database links: Entrez Gene: 83999 Human Omim: 609898 Human SwissProt: Q96MU8 Human Unigene: 229335 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KREMEN1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid