周期素依赖性激酶3抗体
规格：1mg/1ml
英文名： CDK3
别名： Cdk 3; Cell division kinase 3; Cell division protein kinase 3; Cyclin dependent kinase 3; p36; Cdk3; CDK3_HUMAN; CDKN3; Cell division protein kinase 3; Cyclin dependent kinase 3; Cyclin-dependent kina
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CDK3
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Guinea Pig,
细胞定位：
周期素依赖性激酶3抗体产品介绍：background: This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. [provided by RefSeq, Jul 2008] Function: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions.周期素依赖性激酶3抗体 Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner. Subunit: Interacts with CABLES1 and CABLES2. Interacts with ATF1. Binding to CCNC/cyclin-C promotes RB1 phosphorylation. Tissue Specificity: 周期素依赖性激酶3抗体Expressed in cancer cell lines and glioblastoma tissue. Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain. Gene ID: 1018 Database links: Entrez Gene: 1018 Human Omim: 123828 Human SwissProt: Q00526 Human Unigene: 706766 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
周期素依赖性激酶3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid