杀伤细胞凝集素样受体F1抗体
规格:1mg/1ml
英文名: KLRF1
别名: Activating coreceptor NKp80; C type lectin domain family 5 member C; CLEC5C; KLRF1_HUMAN; killer cell lectin like receptor F1; Killer cell lectin like receptor subfamily F member 1; KLRF 1; Lectin lik
分子量: 27kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KLRF1
交叉反应:Human,
细胞定位:细胞膜
杀伤细胞凝集素样受体F1抗体产品介绍:background: KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009] Function: KLRF1 is involved in the natural killer mediated cytolysis of PHA-induced lymphoblasts. Subunit: Homodimer. Subcellular Location: Membrane; Single-pass type II membrane protein Tissue Specificity: Strongly expressed in peripheral blood杀伤细胞凝集素样受体F1抗体 leukocytes and spleen, with weaker expression in lymph node and ***** liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes. Similarity: Contains 1 C-type lectin domain. 杀伤细胞凝集素样受体F1抗体Gene ID: 51348 Database links: Entrez Gene: 51348 Human Omim: 605029 Human SwissProt: Q9NZS2 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
杀伤细胞凝集素样受体F1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 自然杀伤细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid