海藻糖酶抗体
规格:1mg/1ml
英文名: Trehalase
别名: Alpha alpha trehalase; Alpha alpha trehalose glucohydrolase; Alpha; alpha-trehalase; alpha-trehalose glucohydrolase; Brush border membrane glycoprotein; MGC129621; TRE; TREA; TREA_HUMAN; TREH; Trehala
分子量: 64kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Trehalas
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
海藻糖酶抗体产品介绍:background: Trehalase, also known as TREH, TREA or α,α-trehalose glucohydrolase, is a 583 amino acid protein belonging to the glycosyl hydrolase 37 family. Localizing to cell membrane and lipid-anchor, Trehalase is expressed in kidney, liver, and small intestine. Trehalase hydrolyses ingested trehalose, a disaccharide formed by two glucose molecules found mainly in insects, fungi, and plants, into cellular substrate glucose. Isolated trehalose intolerance due to deficiencies of Trehalase can result in gastrointestinal symptoms. Trehalase may also be a marker for renal tubular damage, and may contain an N-terminal signal peptide, five potential N-glycosylation sites, and a海藻糖酶抗体 C-terminal hydrophobic region for glycosylphosphatidylinositol (GPI) attachment. Existing as two alternatively spliced isoforms, the gene encoding Trehalase maps to human chromosome 11q23.3. Function: Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose. Subcellular Location: Cell membrane. DISEASE: Note=Deficiency of TREH results in isolated trehalose intolerance that causes海藻糖酶抗体 gastrointestinal symptoms after ingestion of edible mushrooms. Similarity: Sequence similaritiesBelongs to the glycosyl hydrolase 37 family. Gene ID: 11181 Database links: Entrez Gene: 11181 Human Omim: 275360 Human SwissProt: O43280 Human Unigene: 129712 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
海藻糖酶抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid