生长抑制蛋白5抗体
规格：1mg/1ml
英文名： ING5
别名： 1700001C14Rik; 1700027H23Rik; 1810018M11Rik; FLJ23842; ING 5; ING5; ING5_HUMAN; Inhibitor of growth family member 5; Inhibitor of growth protein 5; p28 ING 5; p28 ING5; p28ING5.
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ING5
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit,
细胞定位：细胞核
生长抑制蛋白5抗体产品介绍：background: The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq, Jul 2008] Function: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component生长抑制蛋白5抗体 of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator. Subcellular Location: Nucleus. Similarity: Belongs to the ING family. Contains 1 生长抑制蛋白5抗体PHD-type zinc finger. Gene ID: 84289 Database links: Entrez Gene: 84289 Human Entrez Gene: 66262 Mouse Entrez Gene: 363292 Rat Omim: 608525 Human SwissProt: Q8WYH8 Human SwissProt: Q9D8Y8 Mouse Unigene: 529172 Human Unigene: 64065 Mouse Unigene: 214030 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
生长抑制蛋白5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid