一氧化氮合成酶相互作用蛋白抗体
规格:1mg/1ml
英文名: NOSIP
别名: CGI 25; CGI-25; NOSIP_HUMAN; CGI25; CGI25 protein; eNOS interacting protein; Nitric oxide synthase interacting protein.
分子量: 33kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NOSIP
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞核 细胞浆
一氧化氮合成酶相互作用蛋白抗体产品介绍:background: The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012] Function: NOSIP is a novel type of modulator that promotes translocation of eNOS from the plasma membrane to intracellular sites, thereby uncoupling eNOS from plasma membrane caveolae and inhibiting NO 一氧化氮合成酶相互作用蛋白抗体synthesis. Subunit: Interacts with NOS1 and NOS3. Subcellular Location: Cytoplasm. Nucleus. Note: Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle. Tissue Specificity: Expressed in heart, brain and lung. Present in endothelial一氧化氮合成酶相互作用蛋白抗体 cells (at protein level). Similarity: Belongs to the NOSIP family. Gene ID: 51070 Database links: Entrez Gene: 51070 Human Entrez Gene: 511234 Cow Entrez Gene: 66394 Mouse Entrez Gene: 292894 Rat SwissProt: Q3SWY5 Cow SwissProt: Q9Y314 Human SwissProt: Q9D6T0 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
一氧化氮合成酶相互作用蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 信号转导 转运蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid