ATP依赖的干扰素反应蛋白1抗体
规格：1mg/1ml
英文名： TOR3A/ADIR2
别名： ADIR; ADIR2; ATP dependant interferon response protein 1; ATP dependant interferon responsive; ATP dependent interferon responsive protein; ATP-dependent interferon-responsive protein; FLJ22345; MGC11
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TOR3A
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆
ATP依赖的干扰素反应蛋白1抗体产品介绍：background: Torsin3A is a 397 amino acid member of the clpA/clpB family of proteins. Localized to the cytoplasm and the endoplasmic reticulum, Torsin3A is most highly expressed in stomach, lymph nodes and salivary glands. Torsin3A contains a hydrophobic N-terminal sequence, an ATP binding domain and 8 putative phosphorylation sites. Highly homologous with TorsinA and TorsinB, Torsin3A is thought to be related to the AAA chaperone-like family of ATPases. Members of this family play a role in the assembly, disassembly and operation of a variety of protein complexes, confer increased tolerance to high temperature and promote specific proteolysis. Torsin3A is also referred to as an interferon responsive gene, as interaction with type 1 interferons (IFN-alpha and IFN-beta) cause a 5 to ATP依赖的干扰素反应蛋白1抗体40 fold increase in Torsin3A mRNA levels. Three isoforms of Torsin3A exist as a result of alternative splicing events, and isoform 2 is expressed exclusively in the placenta Subcellular Location: Cytoplasm. Endoplasmic reticulum. Tissue Specificity: Ubiquitously expressed. Highest expression in stomach, salivary glands and lymph nodes. Isoform 2 is expressed in placenta. Similarity: Belongs to theATP依赖的干扰素反应蛋白1抗体 clpA/clpB family. Torsin subfamily. Gene ID: 64222 Database links: Entrez Gene: 64222 Human Entrez Gene: 30935 Mouse Entrez Gene: 304884 Rat Omim: 607555 Human SwissProt: Q9H497 Human SwissProt: Q9ER38 Mouse SwissProt: Q5M936 Rat Unigene: 584957 Human Unigene: 206737 Mouse Unigene: 2164 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ATP依赖的干扰素反应蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid