热休克因子蛋白5抗体
规格：1mg/1ml
英文名： HSF5
别名： FLJ40311; Heat shock factor protein 5; Heat shock transcription factor 5; Heat shock transcription factor family member 5; HSF 5; HSF5; HSF5_HUMAN; HSTF 5; MGC134827.
分子量： 65kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HSF5
交叉反应：Human,
细胞定位：细胞核
热休克因子蛋白5抗体产品介绍：background: HSF5 is a 596 amino acid protein that localizes to the nucleus and is thought to function as a transcription factor. Multiple isoforms of HSF5 exist due to alternative splicing events. The gene encoding HSF5 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating热休克因子蛋白5抗体 cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic 热休克因子蛋白5抗体determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Function: May act as a transcriptional factor. Subcellular Location: Nucleus. Similarity: Belongs to the HSF family. Gene ID: 124535 Database links: Entrez Gene: 124535 Human SwissProt: Q4G112 Human Unigene: 380061 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
热休克因子蛋白5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid