锌指蛋白674抗体

规格：1mg/1ml

英文名： ZNF674

别名： MENTAL RETARDATION, X LINKED 92; MRX92; ZN674_HUMAN; Zinc finger family member 674; Zinc finger protein 674; ZNF673B.

分子量： 67kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

**原：KLH conjugated synthetic peptide derived from human ZNF674

交叉反应：Human,

细胞定位：细胞核

锌指蛋白674抗体产品介绍：background: This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010] Function: ZNF674 belongs to the krueppel C2H2-type zinc-finger protein family and contains 11 C2H2-type zinc fingers and 1 KRAB domain. ZNF674 may be involved in transcriptional regulation. 锌指蛋白674抗体Defects in ZNF674 may be the cause of mental retardation X-linked type 92 (MRX92). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Subcellular Location: Nuclear Tissue Specificity: Expressed in 锌指蛋白674抗体testis. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 11 C2H2-type zinc fingers. Contains 1 KRAB domain. Gene ID: 641339 Database links: Entrez Gene: 641339 Human Omim: 300573 Human SwissProt: Q2M3X9 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

锌指蛋白674抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：转录调节因子  锌指蛋白  表观遗传学  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid

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