通用转录因子3A
规格：1mg/1ml
英文名： GTF3A
别名： AP 2; AP2; Factor A; General transcription factor 3A; General transcription factor IIIA; GTF 3A; GTF3A; TF3A_HUMAN; TFIIIA; Transcription factor 3A; Transcription factor IIIA.
分子量： 41kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GTF3A
交叉反应：Human,
细胞定位：细胞核
通用转录因子3A产品介绍：background: The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.通用转录因子3A [provided by RefSeq, Jul 2008] Function: Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Similarity: Contains 9 C2H2-type zinc fingers. Gene ID: 2971 Database links: Entrez Gene: 2971 Human Entrez Gene: 66596 Mouse Entrez Gene: 通用转录因子3A246299 Rat Omim: 600860 Human SwissProt: Q92664 Human SwissProt: Q8VHT7 Mouse SwissProt: Q8VHT8 Rat Unigene: 445977 Human Unigene: 358698 Mouse Unigene: 195324 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
通用转录因子3A产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：转录调节因子 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid