谷胱甘肽S转移酶M4抗体
规格：1mg/1ml
英文名： GSTM4
别名： Glutathione S transferase M4; Glutathione S transferase Mu 4; Glutathione S-transferase Mu 4; GST class mu 4; GST class-mu 4; GST-Mu2; GSTM4 4; GSTM4; GSTM4-4; GSTM4_HUMAN; GTM4; GTS Mu2; MGC131945; M
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GSTM4
交叉反应：Human,
细胞定位：细胞浆
谷胱甘肽S转移酶M4抗体产品介绍：background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene谷胱甘肽S转移酶M4抗体 cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified. [provided by RefSeq, Jul 2008] Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Active on 1-chloro-2,4-dinitrobenzene.谷胱甘肽S转移酶M4抗体 Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in a wide variety of tissues. Similarity: Belongs to the GST superfamily. Mu family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain. Gene ID: 2948 Database links: Entrez Gene: 2948 Human GenBank: NM_000850.3 Human Omim: 138333 Human SwissProt: Q03013 Human Unigene: 348387 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
谷胱甘肽S转移酶M4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid