GalNAc-T7蛋白抗体
规格:1mg/1ml
英文名: GALNT7
别名: GalNAc T7; GalNAc-T7; GalNAcT7; GALNT 7; Galnt7; GALT7_HUMAN; N acetylgalactosaminyltransferase 7; N-acetylgalactosaminyltransferase 7; Polypeptide GalNAc transferase 7; Polypeptide N acetylgalactosam
分子量: 75kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GALNT7
交叉反应:Human, Mouse, Rat, Cow, Rabbit, Sheep,
细胞定位:
GalNAc-T7蛋白抗体产品介绍:background: This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation.GalNAc-T7蛋白抗体 [provided by RefSeq, Jul 2008] Function: Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Widely expressed. Expressed in uterus, retina, kidney,GalNAc-T7蛋白抗体 small intestine, omentum, stomach and CNS. Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. Gene ID: 51809 Database links: Entrez Gene: 51809 Human Entrez Gene: 108150 Mouse Entrez Gene: 100171466 Orangutan Entrez Gene: 29750 Rat Omim: 605005 Human SwissProt: Q86SF2 Human SwissProt: Q80VA0 Mouse SwissProt: Q5RFJ6 Orangutan SwissProt: Q9R0C5 Rat Unigene: 548088 Human Unigene: 62886 Mouse Unigene: 207200 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GalNAc-T7蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 跨膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liqui