GalNAc-T5蛋白抗体
规格：1mg/1ml
英文名： GALNT5
别名： GALNAC T5; N acetylgalactosaminyltransferase; Polypeptide GalNAc transferase 5; polypeptide N -acetylgalactosaminyltransferase 5; pp GaNTase 5; Protein UDP acetylgalactosaminyltransferase 5; UDP GalNA
分子量： 106kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GALNT5
交叉反应：Human, Mouse,
细胞定位：细胞膜
GalNAc-T5蛋白抗体产品介绍：background: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T5 (Polypeptide N-acetylgalactosaminyltransferase 5), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5, is a 940 amino acid protein that displays enzymatic activity toward EA2 peptide substrate with weaker activity toward Muc2 or Muc 1b substrates. Its N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. EXT2 directly GalNAc-T5蛋白抗体interacts with GalNAc-T5, suggesting that these proteins may corroborate in glycosaminoglycan synthesis. Function: GALNT5 can catalyze the initial reaction in O-linked oligosaccharide biosynthesis,the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GALNT5 has activity toward EA2 peptide substrate, but it has a weak activity toward Muc2 or Muc1b substrates. Subunit:GalNAc-T5蛋白抗体 Interacts with EXT2. Does not interact with EXT1, EXTL1 or EXTL3. Subcellular Location: Cell Membrane and Golgi Apparatus Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. Gene ID: 11227 Database links: Entrez Gene: 11227 Human Entrez Gene: 241391 Mouse Entrez Gene: 83627 Rat SwissProt: Q7Z7M9 Human SwissProt: Q8C102 Mouse SwissProt: O88422 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GalNAc-T5蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid