γ氨基丁酸受体相关蛋白样3抗体
规格：1mg/1ml
英文名： GABARAPL3
别名： ATG8D; GABA(A) receptor associated protein like 3; GABA(A) receptors associated protein like 3 pseudogene; GABARAPL3; Gamma-aminobutyric acid receptor associated protein-like 3; GBRL3_HUMAN.
分子量： 14kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GABARAPL
交叉反应：Human, Mouse, Rat, Pig, Cow,
细胞定位：
γ氨基丁酸受体相关蛋白样3抗体产品介绍：Function: Ubiquitin-like modifier involved in autophagosome formation. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). Subunit: Interacts with GABRG2 and beta-tubulin (By similarity). Subcellular Location: Cytoplasmic; cytoskeleton (Probable). Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor (Probable). Tissue Specificity: Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus γ氨基丁酸受体相关蛋白样3抗体and small intestine. Post-translational modifications: The precursor molecule is cleaved by ATG4B to form the cytosolic form, GABARAPL3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, GABARAPL3-II. ATG4B also mediates the delipidation required for GABARAPL1 recycling when autophagosomes fuse with lysosomes γ氨基丁酸受体相关蛋白样3抗体(By similarity). Similarity: Belongs to the ATG8 family. Gene ID: 23766 Database links: Entrez Gene: 23766 Human SwissProt: Q9BY60 Human Unigene: 592014 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
γ氨基丁酸受体相关蛋白样3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid