FXL19蛋白抗体
规格:1mg/1ml
英文名: FXL19
别名: F-box and leucine-rich repeat protein 19; F-box/LRR-repeat protein 19; FBL19; Fbxl19; FXL19_HUMAN; JHDM1C; Jumonji C domain containing histone demethylase 1C.
分子量: 76kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FXL19
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:
FXL19蛋白抗体产品介绍:background: This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase FXL19蛋白抗体complex. Subunit: Directly interacts with SKP1 and CUL1 (By similarity). Similarity: Contains 1 CXXC-type zinc finger. Contains 1 F-box domain. Contains 6 LRR (leucine-rich) repeats. Contains 1 PHD-type zinc finger. Gene ID: 54620 Database links: Entrez Gene: 54620 FXL19蛋白抗体Human Entrez Gene: 233902 Mouse Entrez Gene: 308999 Rat GenBank: BC059173 Human Omim: 609085 Human SwissProt: Q6PCT2 Human SwissProt: Q6PB97 Mouse Unigene: 152149 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FXL19蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 跨膜蛋白 泛素
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid