FUS2蛋白抗体
规格：1mg/1ml
英文名： FUS2
别名： AI225910; FUS 2; N acetyltransferase 6; NAT6; NAT6_HUMAN; OTTMUSP00000046403; OTTMUSP00000046404; OTTMUSP00000046405; OTTMUSP00000046406; Protein fus 2; Protein fusion 2.
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FUS2
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
FUS2蛋白抗体产品介绍：background: This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share aFUS2蛋白抗体 portion of the first exon. [provided by RefSeq, Jan 2011] Function: FUS2 seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor. It is strongly expressed in heart and skeletal muscle, followed by brain and pancreas, with weak expression in kidney, liver, and lung and no expression in placenta. Defects in FUS2 are found in non-small cell lung cancer FUS2蛋白抗体(NSCLC) cell lines. Subcellular Location: Cytoplasmic Tissue Specificity: Strongly expressed in heart and skeletal muscle, followed by brain and pancreas, with weak expression in kidney, liver, and lung and no expression in placenta. Similarity: Belongs to the acetyltransferase family. Contains 1 N-acetyltransferase domain. Gene ID: 24142 Database links: Entrez Gene: 24142 Human Omim: 607073 Human SwissProt: Q93015 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FUS2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid