肝黄素单加氧酶1抗体
规格：1mg/1ml
英文名： FMO1
别名： Dimethylaniline monooxygenase [N oxide forming] 1; Dimethylaniline monooxygenase [N-oxide-forming] 1; Dimethylaniline oxidase 1; Fetal hepatic flavin containing monooxygenase 1; Fetal hepatic flavin-c
分子量： 60kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FMO1
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
细胞定位：
肝黄素单加氧酶1抗体产品介绍：background: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in ***** liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Function: This protein is involved in the oxidative metabolism肝黄素单加氧酶1抗体 of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. Subcellular Location: Microsome membrane. Endoplasmic reticulum membrane. Tissue Specificity: Expressed mainly in fetal liver, ***** kidney and, to a lesser extent, the intestine. Similarity: Belongs to the FMO family. Gene ID: 2326 Database links: Entrez Gene: 2326 Human Entrez Gene: 肝黄素单加氧酶1抗体14261 Mouse Entrez Gene: 25256 Rat Omim: 136130 Human SwissProt: Q01740 Human SwissProt: P50285 Mouse SwissProt: P36365 Rat Unigene: 1424 Human Unigene: 976 Mouse Unigene: 867 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肝黄素单加氧酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid