FMNL2蛋白抗体
规格：1mg/1ml
英文名： FMNL2
别名： FHOD2; FHOD1_HUMAN； Formin homology 2 domain containing protein 2; Formin like protein 2; KIAA1902.
分子量： 123kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FMNL2
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Monkey,
细胞定位：细胞浆
FMNL2蛋白抗体产品介绍：background: This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008] Function: This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. Subunit: Self-associates via the FH2 domain. Binds to F-actin via itsFMNL2蛋白抗体 N-terminus. Binds to the cytoplasmic domain of CD21 via its C-terminus. Interacts with ROCK1 in a Src-dependent manner. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, bleb. Note=Predominantly cytoplasmic. Tissue Specificity: Ubiquitous. Highly expressed in spleen. Post-translational modifications: Phosphorylated by ROCK1. Similarity: Belongs to the formin homology familyFMNL2蛋白抗体. Contains 1 DAD (diaphanous autoregulatory) domain. Contains 1 FH1 (formin homology 1) domain. Contains 1 FH2 (formin homology 2) domain. Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. Gene ID: 114793 Database links: Entrez Gene: 114793 Human Entrez Gene: 71409 Mouse Entrez Gene: 311033 Rat SwissProt: Q96PY5 Human SwissProt: A2APV2 Mouse Unigene: 654630 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FMNL2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid