凝集素样蛋白AGRNL抗体
规格：1mg/1ml
英文名： FLJ39155
别名： Agrin-like protein; AGRINL; AGRNL; EGF-like; EGF-like, fibronectin type III and laminin G domains; EGF-like, fibronectin type-III and laminin G-like domain-containing protein; EGFLA_HUMAN; EGFLAM; fib
分子量： 109kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FLJ39155
交叉反应：Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位：细胞浆
凝集素样蛋白AGRNL抗体产品介绍：background: EGFLAM is a 1,017 amino acid secreted protein containing three EGF-like domains, two fibronectin type-III domains, and three laminin G-like domains. Colocalizing with bassoon, CtBP and dystroglycan in photoreceptor synaptic terminals, EGFLAM is involved in retinal photoreceptor ribbon synapse formation. EGFLAM may also promote matrix assembly and cell adhesion. Existing as five alternatively spliced isoforms, the gene encoding EGFLAM maps to human chromosome 5p13.2. Chromosome 5 makes up approximately 6% of the human genome and contains 181 million base pairs, which encode 1,000 genes. Cockayne syndrome, Treacher Collins syndrome, acute myelogenous leukemias and myelodysplastic syndrome are associated with genes present on chromosome 5. Function: Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip 凝集素样蛋白AGRNL抗体apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness. Subcellular Location: Secreted > extracellular space > extracellular matrix. Cell junction > synapse. Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells. Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals. Post-translational modifications: O-glycosylated; contains chondroitin sulfate and heparan sulfate. Similarity: Contains 3 EGF-like domains. Contains 2 fibronectin type-III domains凝集素样蛋白AGRNL抗体. Contains 3 laminin G-like domains. Gene ID: 133584 Database links: Entrez Gene: 133584 Human Entrez Gene: 534427 Cow Entrez Gene: 268780 Mouse Entrez Gene: 365691 Rat SwissProt: A3KN33 Cow SwissProt: Q63HQ2 Human SwissProt: Q4VBE4 Mouse SwissProt: B4F785 Rat Unigene: 20103 Human Unigene: 203208 Mouse Unigene: 27713 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
凝集素样蛋白AGRNL抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 信号转导 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid