FIBIN蛋白抗体
规格:1mg/1ml
英文名: FIBIN
别名: Fibin; FIBIN_HUMAN; Fin bud initiation factor homolog (zebrafish); Fin bud initiation factor homolog; MGC24932; PSEC0235.
分子量: 22kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FIBIN
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆
FIBIN蛋白抗体产品介绍:background: FIBIN (Fin bud initiation factor homolog) is a 211 amino acid protein involved in fin initiation in zebrafish. The human homolog is encoded by a gene that maps to chromosome 11, which makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedemaFIBIN蛋白抗体 and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. Subcellular Location: Secreted. Golgi apparatus. Similarity: Belongs to the FIBIN family. Gene ID: 387758 Database links: Entrez Gene: 387758 Human Entrez Gene: 451086 Chimpanzee Entrez Gene: 507975 Cow Entrez Gene: 100057578 Horse Entrez Gene: 67606 Mouse Entrez Gene: 499856 Rat Entrez Gene: 699699 Rhesus monkey SwissProt:FIBIN蛋白抗体 Q5E9H1 Cow SwissProt: A4UZ23 Horse SwissProt: Q8TAL6 Human SwissProt: Q9CQS3 Mouse SwissProt: Q5U2T4 Rat Unigene: 712718 Human Unigene: 291809 Mouse Unigene: 43451 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FIBIN蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid