FGD1蛋白抗体
规格：1mg/1ml
英文名： FGD1
别名： AAS; Faciogenital dysplasia 1 protein; FGD1; FGD1_HUMAN; FGDY; FYVE RhoGEF and PH domain containing protein 1; FYVE, RhoGEF and PH domain-containing protein 1; Rho/Rac GEF; Rho/Rac guanine nucleotide
分子量： 107kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FGD1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
FGD1蛋白抗体产品介绍：background: Activates CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Function: Activates CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Subcellular Location: Cytoplasm. Cell projection > lamellipodium. Cell projection > ruffle. Cytoplasm > cytoskeleton. Associated with membrane ruffles and lamellipodia. Tissue Specificity: Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; ***** heart, brain, lung, pancreas and FGD1蛋白抗体skeletal muscle. DISEASE: Defects in FGD1 are the cause of Aarskog-Scott syndrome (AAS) [MIM:305400]. This faciogenital dysplasia is a rare multisystemic disorder characterized by disproportionately short stature, and by facial, skeletal, and urogenital anomalies. Note=Defects in FGD1 are found in a pateint with non-syndromal X-linked mental retardation. Similarity: Contains 1 DH (DBL-homology) domain. Contains 1 FYVE-type FGD1蛋白抗体zinc finger. Contains 2 PH domains. Gene ID: 2245 Database links: Entrez Gene: 2245 Human Omim: 305400 Human SwissProt: P98174 Human Unigene: 631767 Human Unigene: 709201 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FGD1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 发育生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid