FbxL7蛋白抗体
规格：1mg/1ml
英文名： FbxL7
别名： AL023057; D230018M15Rik; F Box and Leucine Rich Repeat Protein 7; F box protein FBL6/FBL7; F box/LRR-repeat protein 7; F-box and leucine-rich repeat protein 7; F-box protein FBL6/FBL7; F-box/LRR-repea
分子量： 55kDa
.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FbxL7
交叉反应：Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep,
细胞定位：
FbxL7蛋白抗体产品介绍：background: This gene encodes a member of the F-box protein family which is characterized by a 42-48 amino acid motif, the F-box, which binds to the S-phase kinase-associated protein 1 (Skp1) protein. The F-box proteins constitute one of the four subunits of E3 ubiquitin protein ligases called SCFs (SKP1-Cul1-F-box), which play a role in phosphorylation-dependent ubiquitination of proteins. The F-box proteins are divided into 3 subfamilies based on the other domain in the protein: F-box proteins that also have a WD-40 domainFbxL7蛋白抗体 (Fbws subfamily), F-box proteins that also have leucine-rich repeats (Fbls subfamily) and F-box proteins that contain other motifs or lack known protein-interaction domains (Fbxs subfamily). The protein encoded by this gene belongs to the Fbls subfamily. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013] Function: Probably recognizes and binds to some phosphorylated FbxL7蛋白抗体proteins and promotes their ubiquitination and degradation. Similarity: Contains 1 F-box domain. Contains 11 LRR (leucine-rich) repeats. Gene ID: 23194 Database links: Entrez Gene: 23194 Human Entrez Gene: 448987 Mouse Omim: 605656 Human SwissProt: Q9UJT9 Human SwissProt: Q5BJ29 Mouse Unigene: 433057 Human Unigene: 76798 Human Unigene: 253378 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FbxL7蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 干细胞 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid