嗜酸粒细胞趋化因子/蛋白/Eotaxin抗体
规格：1mg/1ml
英文名： CCL11
别名： Eotaxin 1; C-C motif chemokine 11; CCL 11; CCL11; CCL11_HUMAN; chemokine (C-C motif) ligand 11; Chemokine C C motif ligand 11; Chemokine CC Motif Ligand 11; Chemokine ligand 11; Eosinophil Chemotactic
分子量： 8kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Eotaxin
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆 分泌型蛋白
嗜酸粒细胞趋化因子/蛋白/Eotaxin抗体产品介绍：background: This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Jul 2008]. Function: In response to the presence嗜酸粒细胞趋化因子/蛋白/Eotaxin抗体 of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. Subcellular Location: Secreted. Post-translational modifications: O-linked glycan consists of a Gal-GalNAc disaccharide which is mofified with up to 2 sialic acid residues. Similarity: Belongs to the intercrine beta (chemokine CC) family. Gene ID: 6356 Database 嗜酸粒细胞趋化因子/蛋白/Eotaxin抗体links: Entrez Gene: 6356 Human Omim: 601156 Human SwissProt: P51671 Human Unigene: 54460 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Eotaxin-1嗜酸粒细胞趋化蛋白参与过敏性炎症的嗜酸粒细胞的分化、成熟、内皮粘附和滚动、趋化，参与浸润、活化和释放毒性蛋白，参与炎性介质的过程.
嗜酸粒细胞趋化因子/蛋白/Eotaxin抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid