载脂蛋白H抗体
规格:1mg/1ml
英文名: APOH
别名: Apolipoprotein H; Activated protein C binding protein; APC inhibitor; APOH; B2G1; beta 2 glycoprotein I; beta 2 glycoprotein I precursor; BG; OTTMUSP00000003033; APOH_HUMAN.
分子量: 36kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ApoH
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位:
载脂蛋白H抗体产品介绍:background: Apolipoprotein H is expressed by placental trophoblast cells at high levels. Although the normal physiological role is not known, the protein appears to act as a co-factor for the binding of autoantibodies to phospholipids to trophoblasts, which is a process involved in the pathogenesis of recurrent miscarriage. Function: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on载脂蛋白H抗体 the surface of damaged cells. Subcellular Location: Secreted. Tissue Specificity: Expressed by the liver and secreted in plasma. Post-translational modifications: N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele. Similarity: Contains 载脂蛋白H抗体4 Sushi (CCP/SCR) domains. Gene ID: 350 Database links: Entrez Gene: 350 Human Entrez Gene: 287774 Rat Omim: 138700 Human SwissProt: P02749 Human SwissProt: P26644 Rat Unigene: 445358 Human Unigene: 1824 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 载脂蛋白H(apolipoprotein D,apoH)又称为β2糖蛋白Ⅰ(β2-glycoprotein,β2-GI),是*初是在人血浆的高密度脂蛋白中被分离出来的。apoH在结构上与其他类型的载脂蛋白存在很大的差异,被归入脂肪促成素家族。
载脂蛋白H抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 **学 合成与降解 糖蛋白 脂蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid